Clinico-biochemical prognostic markers in equines with surgical and non- surgical colic

Bassan, Indu Bhushan (2017) Clinico-biochemical prognostic markers in equines with surgical and non- surgical colic. Masters thesis, Sher-E-Kashmir University of Agricultural Sciences and Technology of Jammu.

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36206 Indu Bhushan Bassan MVSc Thesis J-15-MV-427 Veterinary Surgery & Radiology.pdf
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The present study was conducted on twenty four equines suffering from colic presented in the Teaching Veterinary Clinical Complex, F.V.Sc & A.H., S.K.U.A.S.T-J, R.S.Pura, from May 2016 to May 2017. Clinical and hemato-biochemical parameters were studied and peritoneal fluid analysis was done in equines exhibiting signs of abdominal pain. Hospital incidence of equine colic was 31.86 percent (29/91). Age wise highest rate of colic was observed in adult equines of 6-10 years age (54.17 percent) with more prevalence in female (58 percent) as compared to male (42 percent). Physical examination revealed congested mucous membrane, severe abdominal pain, decreased abdominal sound, moderate bowel distension with normal nasogastric reflux, highly significant increased heart rate, respiration rate, capillary refill time and dehydration. Hemato- biochemical studies revealed decreased level of lymphocytes, potassium and calcium; and elevated levels of packed cell volume, blood glucose, blood urea nitrogen and total proteins. Significant decrease in chloride was seen in surgical colic. Mixed acid base balance was found in colicky equines with increased blood pH, tCO2, base excess and bicarbonate in equines presented at 24-48 hours duration of colic. Whereas, decrease in blood pH, tCO2, base excess and bicarbonate was noticed in cases presented at greater than 48 hours of duration of colic. Significant increase in anion gap was observed in surgical colic and non survivor group. Among acute phase proteins, haptoglobin followed by serum amyloid A and fibrinogen showed significant increased levels in colicky equines. Peritoneal fluid analysis revealed abnormal colour and turbidity with increased level of total protein, specific gravity and fibrinogen and decreased level of pH. The results indicated that the clinical variables viz. heart rate, respiration rate, capillary refill time, colour of mucous membrane, degree of pain, colour and turbidity of peritoneal fluid, biochemical variables viz. blood glucose, anion gap and modern inflammatory variables i.e acute phase proteins viz. haptoglobin and fibrinogen may serve as significant prognostic markers for the outcome of survivability in colicky equines.

Item Type: Thesis (Masters)
Additional Information: Registration No. : J-15-MV-427
Uncontrolled Keywords: Anion gap, Colic, Equine, Haptoglobin, Prognostic indicators, Peritoneal fluid
Subjects: S Agriculture > Veterinary Surgery and Radiology
Divisions: Department of Agriculture
Date Deposited: 31 May 2018 07:39
Last Modified: 31 May 2018 07:39

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